DCLK3 - doublecortin like kinase 3 Gene

Also Known as CLR; DCK3; DCDC3C; DCAMKL3

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 85443

About DCLK3

Cytogenetic location: 3p22.2 Genomic coordinates (GRCh38): 3:36,712,421-36,764,553 (from NCBI)

This gene has 3 transcripts (splice variants), 192 orthologues and 22 paralogues. Biased expression in testis (RPKM 2.2), brain (RPKM 0.5) and 6 other tissues.

Summary

Predicted to enable protein kinase activity. Predicted to be involved in peptidyl-serine phosphorylation. Predicted to act upstream of or within negative regulation of protein localization to nucleus. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

DCLK3 Products (2)

mRNA Protein Name
NM_001394672.2 NP_001381601.1 serine/threonine-protein kinase DCLK3 isoform 1
NM_033403.1 NP_208382.1 serine/threonine-protein kinase DCLK3 isoform 2

DCLK3 Protein Structure

Pkinase

Pkinase: Protein kinase domain (356 - 613)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 600
  • 648 a.a.
Protein Preferred Names Protein Names

serine/threonine-protein kinase DCLK3

  • CLICK-I,II-related

関連疾患

Diseases Alias
Multidrug-Resistant Tuberculosis

  • Tuberculosis, Multidrug-Resistant

  • Tuberculosis Multidrug-Resistant
Neutropenia, Severe Congenital, X-Linked

  • X-Linked Severe Congenital Neutropenia

  • XLN

  • SCNX

  • Severe Congenital Neutropenia X-Linked

  • Neutropenia, Congenital, Severe, X-Linked
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS03580 DCLK3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Bos taurus DCLK3 VGNC VGNC:59331
Mus musculus DCLK3 MGD MGI:3039580
Felis catus DCLK3 VGNC VGNC:61369
Macaca mulatta DCLK3 VGNC VGNC:71671
Rattus norvegicus DCLK3 RGD RGD:1309232
Canis familiaris DCLK3 VGNC VGNC:39805
Others DCLK3 NCBI