MtMetAP1-IN-1
MtMetAP1-IN-1 is an inhibitor of Mycobacterium tuberculosis (Mtb), targeting methionine aminopeptidase 1 (MetAP1). MtMetAP1-IN-1 exerts antimycobacterial activity.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C15H10BrN5O2S
- 分子量:404.24
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
methionine aminopeptidase 1 (MetAP1)[1]
MetAP1 is known to work in the presence of various divalent cations, is considered to acts function with a most probable cofactor, iron (Fe2+)[1].
MtMetAP1-IN-1 (compound 12) (12.5 μM) inhibits MtMetAP1 under different metals catalytic effect with residual activity RA (%) of 51% (Co2+), 21% (Ni2+), 33% (Fe2+)[1].
MtMetAP1-IN-1 has a preference towards Ni2+, inhibits MtMetAP1 with an IC50 value of with 0.7 μM [1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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分子量 404.24
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分子式 C15H10BrN5O2S
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SMILES
O=C(C1=NC=CN=C1NC(C2=C(C=CC=C2)Br)=O)NC3=NC=CS3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
MtMetAP1-IN-1 関連分類
HY-143249 関連分類
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