SENP1-IN-2
SENP1-IN-2 is a specific deSUMOylation protease 1 (SENP1) inhibitor extracted from patent CN110627860, Compound 30. SENP1-IN-2 is developed for tumor radiosensitivity enhancement.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2416910-70-6
- 分子式: C36H60N2O5
- 分子量:600.87
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
SENP1[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
>20 μM
Compound: 43
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Cytotoxicity against human HeLa cells assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay
Cytotoxicity against human HeLa cells assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay
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[PMID: 34688014] |
SENP1-IN-2 may improve the sensitivity of tumor cells to irradiation[1].
SENP1-IN-2 (0.7-20 μM; 72 hours) has cytotoxic for Hella cells with an IC50 of >20 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Hela cells
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Concentration:0.7 μ M, 2.2 μM, 6.6 μM, 20 μM
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Incubation Time:72 hours
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Result:IC50>20 μM
化学情報
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CAS 番号 2416910-70-6
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分子量 600.87
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分子式 C36H60N2O5
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SMILES
CC1(C)[C@@H](O)CC[C@]2(C)[C@@]3([H])CC=C4[C@]5([H])[C@@H](C)[C@H](C)CC[C@@](C(NCC(N(CCO)CCO)=O)=O)5CC[C@](C)4[C@@](C)3CC[C@@]12[H]
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
SENP1-IN-2 関連分類
HY-134595 関連分類
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