Ccn1 - cellular communication network factor 1 Gene

Also Known as Cyr61

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 83476

Summary

Predicted to enable extracellular matrix binding activity; heparin binding activity; and Integrin binding activity. Involved in cell adhesion; chemotaxis; and positive regulation of cytokine production. Predicted to be located in extracellular region. Predicted to be active in extracellular matrix. Orthologous to human CCN1 (cellular communication network factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Ccn1 Products (1)

mRNA Protein Name
NM_031327.3 NP_112617.3 CCN family member 1 precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in cell adhesion IDA
IDA: Inferred from direct assay
11897702 RGD
involved in cellular response to angiotensin IEP
IEP: Inferred from expression pattern
15117851 RGD
involved in cellular response to hypoxia IEP
IEP: Inferred from expression pattern
30371213 RGD
involved in cellular response to norepinephrine stimulus IEP
IEP: Inferred from expression pattern
15117851 RGD
involved in cellular response to tumor necrosis factor IEP
IEP: Inferred from expression pattern
15117851 RGD
involved in chemotaxis IDA
IDA: Inferred from direct assay
11897702 RGD
involved in positive regulation of cellular senescence IEP
IEP: Inferred from expression pattern
30371213 RGD
involved in positive regulation of chemokine (C-X-C motif) ligand 2 production IMP
IMP: Inferred from mutant phenotype
27653023 RGD
involved in positive regulation of interleukin-1 beta production IMP
IMP: Inferred from mutant phenotype
27653023 RGD
involved in positive regulation of interleukin-17 production IMP
IMP: Inferred from mutant phenotype
27653023 RGD
involved in positive regulation of interleukin-6 production IMP
IMP: Inferred from mutant phenotype
27653023 RGD
involved in positive regulation of tumor necrosis factor (ligand) superfamily member 11 production IMP
IMP: Inferred from mutant phenotype
27653023 RGD
involved in positive regulation of tumor necrosis factor production IMP
IMP: Inferred from mutant phenotype
27653023 RGD
Cellular Component GO Annotation Evidence References Source
located in cytosol IDA
IDA: Inferred from direct assay
15117851 RGD
located in membrane IDA
IDA: Inferred from direct assay
15117851 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

CCN family member 1

  • IBP-10

  • IGF-binding protein 10

  • IGFBP-10

  • cysteine rich protein 61

  • cysteine-rich, angiogenic inducer, 61

  • insulin-like growth factor-binding protein 10

  • protein CYR61

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02117 CCNA2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-181537 PROTAC TEAD1/IAP degrader-2 / Unkown
HY-184179 TEAD degrader-1 Degrader / Unkown
HY-RS02110 CCN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11023 PPP3CA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17949 Ccn1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18168 Ccna2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24420 Ccn1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ccn1 NCBI NCBI:3491