S100A16 - S100 calcium binding protein A16 Gene

Also Known as AAG13; S100F; DT1P1A7

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 140576

About S100A16

Cytogenetic location: 1q21.3 Genomic coordinates (GRCh38): 1:153,606,883-153,613,137 (from NCBI)

This gene has 5 transcripts (splice variants), 205 orthologues and 21 paralogues. Biased expression in esophagus (RPKM 418.9), skin (RPKM 89.4) and 13 other tissues.

Summary

Enables calcium ion binding activity and protein homodimerization activity. Predicted to act upstream of or within response to calcium ion. Located in several cellular components, including cytosol; extracellular space; and nucleolus. [provided by Alliance of Genome Resources, Apr 2022]

S100A16 Products (3)

mRNA Protein Name
NM_001317007.1 NP_001303936.1 protein S100-A16
NM_001317008.2 NP_001303937.1 protein S100-A16
NM_080388.3 NP_525127.1 protein S100-A16

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables calcium ion binding IDA
IDA: Inferred from direct assay
17030513 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
enables protein homodimerization activity IPI
IPI: Inferred from physical interaction
17030513 GOA
Cellular Component GO Annotation Evidence References Source
located in cytosol IDA
IDA: Inferred from direct assay
17030513 GOA
located in extracellular space IDA
IDA: Inferred from direct assay
21805676 GOA
located in nucleolus IDA
IDA: Inferred from direct assay
17030513 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

S100A16 Protein Structure

EF-hand_7

EF-hand_7: EF-hand domain pair (31 - 79)

  • 0
  • 103 a.a.
Protein Preferred Names Protein Names

protein S100-A16

  • aging-associated gene 13 protein

S100A16 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
S100A16 Q96FQ6 S100A14 Homo sapiens Q9HCY8
Validated Y2H
32296183
Intra
S100A16 Q96FQ6 S100A14 Homo sapiens Q9HCY8
Y2H Array
32296183
Intra
S100A16 Q96FQ6 S100A14 Homo sapiens Q9HCY8
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant S100A16 Proteins

Cat. No. 상품명 Accession Purity
HY-P71273 S100A16 Protein, Human Q96FQ6 (M1-S103) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. 상품명
효과
Purity
Rare Diseases
HY-RS06372 HRNR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12377 S100A16 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18106 S100a16 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24580 S100a16 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus S100A16 VGNC VGNC:34241
Canis familiaris S100A16 VGNC VGNC:45827
Rattus norvegicus S100A16 RGD RGD:1306770
Macaca mulatta S100A16 VGNC VGNC:100127
Mus musculus S100A16 MGD MGI:1915110
Others S100A16 NCBI