Senp7 - SUMO1/sentrin specific peptidase 7 Gene

Also Known as 2410152H17Rik; 2810413I22Rik; 2900036C23Rik; 6030449K19Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 66315

Summary

This gene encodes a SUMO deconjugating enzyme of the Sentrin/SUMO-specific protease (SENP) family. The encoded protein is a protease that exhibits deSUMOylating activity towards proteins involved in chromatin remodeling and promotes chromatin relaxation for DNA repair or transcription. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2015]

Senp7 Products (5)

mRNA Protein Name
NM_001003972.2 NP_001003972.1 sentrin-specific protease 7 isoform 3
NM_001003973.2 NP_001003973.1 sentrin-specific protease 7 isoform 4
NM_001304503.1 NP_001291432.1 sentrin-specific protease 7 isoform 5
NM_001360073.1 NP_001347002.1 sentrin-specific protease 7 isoform 6
NM_025483.4 NP_079759.2 sentrin-specific protease 7 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables SUMO-specific endopeptidase activity IDA
IDA: Inferred from direct assay
28095500 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
22388734 MGI
Biological Process GO Annotation Evidence References Source
involved in antiviral innate immune response IDA
IDA: Inferred from direct assay
28095500 MGI
involved in protein desumoylation IDA
IDA: Inferred from direct assay
28095500 MGI
Cellular Component GO Annotation Evidence References Source
is active in cytoplasm IDA
IDA: Inferred from direct assay
28095500 MGI
is active in postsynaptic cytosol IDA
IDA: Inferred from direct assay
33113832 MGI
is active in presynaptic cytosol IDA
IDA: Inferred from direct assay
33113832 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sentrin-specific protease 7

  • SUMO-1-specific protease 2

  • SUMO1/sentrin specific protease 7

  • sentrin/SUMO-specific protease SENP7

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. 상품명
효과
Purity
Rare Diseases
HY-RS12676 SENP7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19740 Senp7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26236 Senp7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Senp7 NCBI NCBI:57337