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Cat. No.: HY-123977

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RasGRP3 ligand 1

RasGRP3 ligand 1 (compound 96) is a RasGRP3 ligand with a K_i of 1.75 nM. RasGRP3 ligand 1 can induce Ras activation and can be used for cancer research.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 2229068-13-5
화학식: C₂₁H₂₅NO₅
분자량:371.43

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

RasGRP3 ligand 1 Chemical Structure

CAS No.: 2229068-13-5

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

RasGRP3 ligand 1 (compound 96) is a RasGRP3 ligand with a K_i of 1.75 nM. RasGRP3 ligand 1 can induce Ras activation and can be used for cancer research^[1].

All Ras Isoforms :

In Vitro

RasGRP3 ligand 1 (1-10000 nM, 30 min) activates Ras in a dose dependent manner in RasGRP over expressing HEK293, LNCaP and Ramos cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2229068-13-5
분자량 371.43
화학식 C₂₁H₂₅NO₅
SMILES

CN1C2=CC=CC=C2C(/C=C3CC(CO)(OC\3=O)COC(C(C)(C)C)=O)=C1
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ann J, et al. α-Arylidene Diacylglycerol-Lactones (DAG-Lactones) as Selective Ras Guanine-Releasing Protein 3 (RasGRP3) Ligands. J Med Chem. 2018 Jul 26;61(14):6261-6276. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

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Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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