1. Apoptosis
  2. Bcl-2 Family
  3. Mcl1-IN-8

Mcl1-IN-8 

Cat. No.: HY-122627
Handling Instructions

Mcl1-IN-8 (Comp8) is a Mcl-1-PUMA interface inhibitor, with a Ki of 0.3 μM. Mcl1-IN-8 (Comp8) exhibits dual activity on reduce PUMA-dependent apoptosis while deactivating Mcl-1-mediated anti-apoptosis in cancer cells.

For research use only. We do not sell to patients.

Mcl1-IN-8 Chemical Structure

Mcl1-IN-8 Chemical Structure

CAS No. : 678158-55-9

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Description

Mcl1-IN-8 (Comp8) is a Mcl-1-PUMA interface inhibitor, with a Ki of 0.3 μM. Mcl1-IN-8 (Comp8) exhibits dual activity on reduce PUMA-dependent apoptosis while deactivating Mcl-1-mediated anti-apoptosis in cancer cells[1].

IC50 & Target[1]

Mcl-1

0.3 μM (Ki)

Molecular Weight

393.50

Formula

C₂₂H₂₃N₃O₂S

CAS No.

678158-55-9

SMILES

O=C1N=C(N2CCN(CCO)CC2)S/C1=C\C3=CC=C(C4=CC=CC=C4)C=C3

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Room temperature in continental US; may vary elsewhere

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Mcl1-IN-8
Cat. No.:
HY-122627
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