Anti-Mouse Vβ8 TCR Antibody (F23.1)
Anti-Mouse Vβ8 TCR Antibody (F23.1) is an anti-mouse Vβ8 TCR IgG2a monoclonal antibody. Anti-Mouse Vβ8 TCR Antibody (F23.1) can clear Vβ8+ T cells to alleviate immune conditions. Anti-Mouse Vβ8 TCR Antibody (F23.1) can be used for research on autoimmune conditions. Anti-Mouse Vβ8 TCR Antibody (F23.1) is often used in flow cytometry.
For research use only. We do not sell to patients.
- Molecular Weight:150 kDa
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Mouse IgG2a kappa
Mouse
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Female MRL/Mp-lpr/lpr mice[1]
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Dosage:100 μg
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Administration:Intraperitoneal injection (i.p.), twice every 2 days, for 10-12 weeks
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Result:Significantly prolonged the survival period.
Reduced proteinuria concentration, incidence of arthritis and skin ulcers.
Significantly reduced the accumulation of Vβ8+ and CD4-CD8- T cells.
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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Product Image
Flow cytometry
Chemical Information
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Molecular Weight 150 kDa
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SMILES
[Anti-Mouse Vβ8 TCR Antibody (F23.1)]
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. de Alborán IM, et al. Attenuation of autoimmune disease and lymphocyte accumulation in MRL/lpr mice by treatment with anti-V beta 8 antibodies. Eur J Immunol. 1992 Aug;22(8):2153-8. [Content Brief]
[2]. Yang Y, et al. Focused specificity of intestinal TH17 cells towards commensal bacterial antigens. Nature. 2014 Jun 5;510(7503):152-6. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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