Chemical constituents of Thai propolis

  • Fitoterapia. 2013 Jul:88:96-100. doi: 10.1016/j.fitote.2013.04.008.
Sirivan Athikomkulchai  1 ,  Suresh Awale  2 ,  Nijsiri Ruangrungsi  3 ,  Somsak Ruchirawat  4 ,  Shigetoshi Kadota  5
Affiliations
  • 1. Faculty of Pharmacy, Srinakharinwirot University, Nakhon nayok, 26120, Thailand.
  • 2. Frontier Research Core for Life Sciences, University of Toyama, 2630-Sugitani, Toyama 930-0194, Japan; Institute of Natural Medicine, University of Toyama, 2630-Sugitani, Toyama 930-0194, Japan. Electronic address: [email protected].
  • 3. Faculty of Pharmaceutical Sciences and College of Public Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
  • 4. Chulabhorn Research Institute, Vipavadee Rangsit Highway, Bangkok 10210, Thailand; Chemical Biology Program, Chulabhorn Graduate Institute, and the Center for Environmental Health, Toxicology and Management of Chemicals (ETM), Thailand.
  • 5. Institute of Natural Medicine, University of Toyama, 2630-Sugitani, Toyama 930-0194, Japan.
PMID: 23660244 DOI: 10.1016/j.fitote.2013.04.008
Abstract

Phytochemical investigation on the constituents of Thai propolis led the isolation of a new phenylallylflavanone, (7″S)-8-[1-(4'-hydroxy-3'-methoxyphenyl)prop-2-en-1-yl]-(2S)-pinocembrin (1) and (E)-cinnamyl-(E)-cinnamylidenate (2) from methanolic extract of Thai propolis. Their structures were determined on the basis of extensive NMR spectroscopic analysis. In addition to this, 19 compounds (3-21) belonging to Flavonoids and phenolic esters were isolated and identified.

Keywords
Flavanoids; Phenolic esters; Phenylallylflavanones; Thai propolis.
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