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Cdkn2a

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  • HY-P72785
    CDKN2A Protein, Human

    Cyclin-dependent kinase inhibitor 2a; CDK4I; MTS-1; p16INK4A

    		 Human E. coli
    CDKN2A Protein, a potent negative regulator of cell proliferation, forms strong interactions with CDK4 and CDK6, hindering their association with cyclins D and retinoblastoma protein phosphorylation. Acting in a heterodimeric manner, predominantly with CDK6, CDKN2A inhibits cyclin D-CDK4 kinase activity and interacts with ISCO2, contributing to its cell cycle regulatory role. CDKN2A Protein, Human is the recombinant human-derived CDKN2A protein, expressed by E. coli , with tag free.

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