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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
MDOA
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "MDOA" in MCE Product Catalog:
製品番号: HY-W327840
CAS 番号: 4088-22-6
別名: Dioctadecylmethylamine; MDOA
N-Methyldioctadecylamine (Dioctadecylmethylamine; MDOA) is a surfactant and an ionizable cationic helper lipid that can be used for the preparation of lipid nanoparticles. When used in combination with iPhos 9A1P9 (HY-W590683) in ionizable lipid nanoparticles (iPLNPs), N-Methyldioctadecylamine enables liver-selective mRNA expression. N-Methyldioctadecylamine supports initial in vitro and in vivo mRNA delivery screening for iPhos lipids .
製品番号: HY-185751
CAS 番号: 2760467-77-2
10A1P16 is an ionizable phospholipid composed of a tertiary amine, a phosphate group and three hydrophobic tails. As a spleen-selective RNA delivery vector, 10A1P16 successfully transfects approximately 30% of splenic macrophages and 6% of splenic B cells in vivo. 10A1P16 can be used to prepare spleen-selective 10A1P16-MDOA lipid nanoparticles, which effectively mediate mRNA delivery and gene editing in mouse models. This delivery system retains potent spleen-targeted mRNA delivery efficacy and can be applied to ovarian cancer research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
