1 Result for "

1616632-77-9

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "1616632-77-9" in MCE Product Catalog:

10
10 Cited Publications
Cat. No.: HY-15615A
CAS No.: 1616632-77-9
Purity:  99.89%
Synonyms: TIC10; ONC-201
Target:  

TNF Receptor Apoptosis

Research Areas:  

Cancer

Dordaviprone (TIC10) is a potent, orally active, and stable tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) inducer which acts by inhibiting Akt and ERK, consequently activating Foxo3a and significantly inducing cell surface TRAIL. Dordaviprone can cross the blood-brain barrier .
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