1 Result for "

3082166-76-2

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "3082166-76-2" in MCE Product Catalog:

Cat. No.: HY-173629
CAS No.: 3082166-76-2
Target:  

Ras Apoptosis

Research Areas:  

Cancer

RMC-5127 is a small molecule inhibitor that binds to GTP-targeted KRAS G12V, with oral bioavailability and blood-brain barrier permeability. RMC-5127 inhibits the activities of the RAS and MAPK pathways, suppresses the proliferation of KRAS G12V-mutant cancer cells and induces their apoptosis. RMC-5127 can be used for the research of KRAS G12V-mutant non-small cell lung cancer, pancreatic ductal adenocarcinoma, colorectal cancer and intracranial KRAS G12V tumors .
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