1 Result for "

5-HT4a

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "5-HT4a" in MCE Product Catalog:

Cat. No.: HY-14152
CAS No.: 179474-80-7
Target:  

5-HT Receptor

Research Areas:  

Cancer

Prucalopride hydrochloride is an orally active, selective and specific 5-HT4 receptor agonist (high affinity), with pKis of 8.6 and 8.1 for human 5-HT4a/4b receptors, respectively. Prucalopride hydrochloride improves intestinal motility by promoting regeneration of the intestinal nervous system in rats. Prucalopride hydrochloride also shows anticancer activity by blocking of the PI3K/AKT/mTor signaling pathway. Prucalopride hydrochloride can be used in studies of chronic constipation, pseudo-intestinal obstruction and cancer .
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