1 Result for "

6bK formate

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "6bK formate" in MCE Product Catalog:

Cat. No.: HY-110197A
Target:  

IDE

Research Areas:  

Metabolic Disease

6bK formate is a selective insulin-degrading enzyme (IDE) inhibitor with an IC50 of 50 nM. 6bK formate binds to the distal pocket of IDE, thereby blocking substrate binding, peptide unfolding and cleavage processes, and reducing the degradation of insulin, glucagon and amylin. 6bK formate improves oral glucose tolerance but impairs intraperitoneal glucose tolerance. 6bK formate can be used in research related to type 2 diabetes .
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