1 Result for "

78739-01-2

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "78739-01-2" in MCE Product Catalog:

Cat. No.: HY-100781
CAS No.: 78739-01-2
Synonyms: D-APB; D-2-Amino-4-phosphonobutyric acid
Target:  

iGluR

Research Areas:  

Neurological Disease

D-AP4 (D-APB; D-2-Amino-4-phosphonobutyric acid), a phosphono analogue of glutamate, is an NMDA broad spectrum excitatory amino acid receptor antagonist. D-AP4 also is an agonist for a quisqualate-sensitized AP6 site in hippocampus. D-AP4 inhibits AMPA receptor-stimulated 57Co 2+ influx in cultured cerebellar granule cells (IC50 ≥ 100 μM) .
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