1 Result for "

890090-75-2

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "890090-75-2" in MCE Product Catalog:

Cat. No.: HY-10029A
CAS No.: 890090-75-2
Synonyms: (Rac)-Rebemadlin
Research Areas:  

Cancer

(Rac)-Nutlin-3 (Rebemadlin), an active enantiomer of Nutlin-3, is a potent murine double minute (MDM2) inhibitor (IC50=90 nM). (Rac)-Nutlin-3 inhibits MDM2-p53 interactions and stabilizes the p53 protein, and induces cell autophagy and apoptosis. (Rac)-Nutlin-3 has the potential for the study of TP53 wild-type ovarian carcinomas .
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