1 Result for "

A371191

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "A371191" in MCE Product Catalog:

Cat. No.: HY-122275
CAS No.: 406228-58-8
Target:  

Bcl-2 Family

Research Areas:  

Cancer

A-371191 is a selective Bcl-XL antagonist with a Ki <0.5 μM, and also acts as a mitochondria-targeting agent and chemosensitizer. A-371191 restores the sensitivity of cancer cells overexpressing Bcl-XL to Cisplatin (HY-17394) and Doxorubicin (HY-15142A). A-371191 reduces tumor volume in mice with intraperitoneal tumors. A-371191 can be used in the research of acute myeloid leukemia .
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