1 Result for "

ABD350

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ABD350" in MCE Product Catalog:

Cat. No.: HY-118668
CAS No.: 1117772-52-7
Target:  

NF-κB

Domaines de recherche:  

Others

ABD-350 is an antiresorptive agent that inhibits osteoclast activity without affecting osteoblast activity and preventing ovariectomy-induced bone loss. ABD-350 inhibits NF-κB ligand-induced inhibitor of NF-κB phosphorylation, leading to osteoclast apoptosis, but has no inhibitory effect on osteoblast function, effectively preventing bone loss in ovariectomized mice, and does not inhibit parathyroid hormone-induced bone formation.
loading...
    loading...