6 Results for "

ABT-378

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "ABT-378" in MCE Product Catalog:

20
20 Cited Publications
Cat. No.: HY-14588
CAS No.: 192725-17-0
Purity:  99.71%
Synonyms: ABT-378
Target:  

HIV HIV Protease SARS-CoV

Research Areas:  

Infection Neurological Disease Cancer

Lopinavir (ABT-378) is a highly potent, selective peptidomimetic inhibitor of the HIV-1 protease, with Kis of 1.3 to 3.6 pM for wild-type and mutant HIV protease. Lopinavir acts by arresting maturation of HIV-1 thereby blocking its infectivity . Lopinavir is also a SARS-CoV 3CL pro inhibitor with an IC50 of 14.2 μM .
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Cat. No.: HY-14588R
CAS No.: 192725-17-0
Synonyms: ABT-378 (Standard)
Research Areas:  

Infection Cancer

Lopinavir (Standard) is the analytical standard of Lopinavir. This product is intended for research and analytical applications. Lopinavir (ABT-378) is a highly potent, selective peptidomimetic inhibitor of the HIV-1 protease, with Kis of 1.3 to 3.6 pM for wild-type and mutant HIV protease. Lopinavir acts by arresting maturation of HIV-1 thereby blocking its infectivity . Lopinavir is also a SARS-CoV 3CL pro inhibitor with an IC50 of 14.2 μM .
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Cat. No.: HY-14588S1
CAS No.: 1224729-35-4
Lopinavir-d8 (ABT-378-d8) is the deuterium labeled Lopinavir. Lopinavir (ABT-378) is a highly potent, selective peptidomimetic inhibitor of the HIV-1 protease, with Kis of 1.3 to 3.6 pM for wild-type and mutant HIV protease. Lopinavir acts by arresting maturation of HIV-1 thereby blocking its infectivity . Lopinavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 14.2 μM .
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Cat. No.: HY-14588S
CAS No.: 1322625-54-6
Synonyms: (rel)-ABT-378-d8
(rel)-Lopinavir-d8 ((rel)-ABT-378-d8) is the deuterium labeled Lopinavir (HY-14588) . Lopinavir (ABT-378) is a highly potent, selective peptidomimetic inhibitor of the HIV-1 protease, with Kis of 1.3 to 3.6 pM for wild-type and mutant HIV protease. Lopinavir acts by arresting maturation of HIV-1 thereby blocking its infectivity . Lopinavir is also a SARS-CoV 3CL pro inhibitor with an IC50 of 14.2 μM .
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Cat. No.: HY-14588S2
CAS No.: 1432060-78-0
Synonyms: ABT-378-d7
Lopinavir-d7 is deuterated labeled Lopinavir (HY-14588). Lopinavir (ABT-378) is a highly potent, selective peptidomimetic inhibitor of the HIV-1 protease, with Kis of 1.3 to 3.6 pM for wild-type and mutant HIV protease. Lopinavir acts by arresting maturation of HIV-1 thereby blocking its infectivity . Lopinavir is also a SARS-CoV 3CL pro inhibitor with an IC50 of 14.2 μM .
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Cat. No.: HY-14588A
CAS No.: 1798014-18-2
Synonyms: (rel)-ABT-378
Target:  

Drug Intermediate

Research Areas:  

Others

rel-Lopinavir ((rel)-ABT-378) is a drug impurity.
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