1 Result for "

AKE-72

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "AKE-72" in MCE Product Catalog:

Cat. No.: HY-157327
CAS No.: 2566525-18-4
Purity:  98.29%
Target:  

Bcr-Abl

Research Areas:  

Cancer

AKE-72 (compound 5) is a potent inhibitor of Pan-BCR-ABL. AKE-72 inhibits BCR-ABL WT, BCR-ABL T315, BCR-ABL E255K, BCR-ABL F3171, BCR-ABL H396P and BCR-ABL Q252H with IC50s of < 0.5, 9, 8.98, 3.12, < 1.0 and 3.88 nM, respectively. AKE-72 has anti-leukemic activity against K-562 cell line .
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