1 Result for "

ALK-IN-23

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ALK-IN-23" in MCE Product Catalog:

Cat. No.: HY-151155
CAS No.: 3033549-18-4
Research Areas:  

Cancer

ALK-IN-23 is a potent ALK inhibitor with IC50 values of 1.6 nM, 0.71 nM and 1.3 nM for ALK WT, ALK L1196M and ALK G1202R. ALK-IN-23 can block cell cycle in G2 phase and induce apoptosis. ALK-IN-23 inhibits cancer cell migration and colony formation in vitro. ALK-IN-23 exhibits antitumor activity in H2228 xenograft nude mice model with hypotoxicity .
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