1 Result for "

ALK-expressing cells

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ALK-expressing cells" in MCE Product Catalog:

Cat. No.: HY-117806
CAS No.: 1388225-79-3
Research Areas:  

Cancer

TSR-011-isomer is an isomer of Belizatinib (HY-17603), a ALK inhibitor with an IC50 of 6 nM. TSR-011-isomer acts as a substrate for metabolic hydrolysis and NADPH-dependent metabolism. TSR-011-isomer undergoes enzymatic hydrolysis in mouse plasma and NADPH-dependent metabolism in mouse liver microsomes, thereby supporting clearance processes. TSR-011-isomer can be used in studies related to ALK-driven cancers .
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