1 Result for "

APP-CHO cells

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "APP-CHO cells" in MCE Product Catalog:

Cat. No.: HY-184474
Target:  

LXR PPAR

Research Areas:  

Neurological Disease

AU403 is a potent, brain-penetrant, isoform-selective LXRβ/PPARδ dual agonist (EC50 ≈ 45 nM for LXRβ and EC50 ≈ 40 nM for PPARδ). AU403 is designed to bypass LXRα-driven hepatotoxicity. AU403 significantly improves cognitive functions and reduces amyloid-β plaque burden in 3xTg-AD mice. AU403 is a promising dual-acting agonist for the research of Alzheimer’s disease .
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