1 Result for "

APVO436

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "APVO436" in MCE Product Catalog:

Cat. No.: HY-P990928
CAS No.: 2839556-21-5
Synonyms: APVO-436

Target:  

CD3 Interleukin Related

Research Areas:  

Inflammation/Immunology Cancer

Mipletamig (APVO-436) is a bispecific CD123 x CD3 monoclonal antibody. Mipletamig simultaneously binds to both CD3-expressing T cells and CD123-expressing cancer cells, thereby crosslinking CD123-expressing tumor cells and cytotoxic T lymphocytes (CTLs). This results in the activation and proliferation of T-cells and causes CTL-mediated cell lysis of CD123-expressing tumor cells. Mipletamig can be used for the study of acute myeloid leukemia (AML) .
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