1 Result for "

ARG878

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ARG878" in MCE Product Catalog:

Cat. No.: HY-181460
Target:  

HyT PARP

Research Areas:  

Cancer

PARP1 degrader-2 (Compound 11e) is a potent, selective PARP1 HYT degrader (DC50: 2.16 μM). PARP1 degrader-2 selectively binds to and degrades PARP1 but not PARP2. PARP1 degrader-2 mediates the degradation of PARP1 via the ubiquitin-proteasome system (UPS). PARP1 degrader-2 exhibits anticancer activity against triple-negative breast cancer and colon cancer (hydrophobic tag: (HY-W022007); PARP1 ligand: (HY-75706); Linker: (HY-W015300)) .
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