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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
ATG8
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "ATG8" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-W250118
CAS No.: 90989-93-8
Cat. No.: HY-P83137A
Synonyms: ATG8; GEF2; ATG8C; GEF-2; GATE16; GATE-16
Cat. No.: HY-183807
CAS No.: 2841473-81-0
T1742 is an autophagy inhibitor targeting ATG5. T1742 blocks and disrupts protein-protein interactions between ATG5 and ATG16L1, and between ATG5 and TECAIR.T 1742 inhibits autophagy in living cells via reduced autophagosome formation and downregulated ATG8-PE conjugation. T1742 can be used to study autophagy mechanisms .
Cat. No.: HY-RS18108
Target:
Research Areas:
Map1lc3b Mouse Pre-designed siRNA Set A contains three designed siRNAs for Map1lc3b gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-183826
CAS No.: 2841473-91-2
ATG5 PPI-IN-4 is an autophagy inhibitor targeting ATG5, with an IC50 of 12.78 μM against ATG5-ATG16L1 and an IC50 of 12.00 μM against ATG5-TECAIR. ATG5 PPI-IN-4 blocks the protein interactions between ATG5 and ATG16L1, as well as between ATG5 and TECAIR, disrupts the assembly of the ATG12-ATG5-ATG16L1 ternary complex, inhibits the lipidation modification of LC3/ATG8, and ultimately downregulates cellular autophagy levels. ATG5 PPI-IN-4 can be used in autophagy-related research, such as studies on infection and cancer .
Cat. No.: HY-RS05202
Target:
Research Areas:
GABARAPL1 Human Pre-designed siRNA Set A contains three designed siRNAs for GABARAPL1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS05203
Target:
Research Areas:
GABARAPL2 Human Pre-designed siRNA Set A contains three designed siRNAs for GABARAPL2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
