1 Result for "

ATR-IN-20

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ATR-IN-20" in MCE Product Catalog:

Cat. No.: HY-151915
CAS No.: 3012609-63-8
Target:  

ATM/ATR mTOR

Research Areas:  

Cancer

ATR-IN-20 is a potent ATR (ATM/ATR) inhibitor with an IC50 of 3 nM. ATR-IN-20 possess an inhibitory effect on mTOR (IC50 of 18 nM) while displaying good selectivity against PI3Kα (100 nM), ATM (100 nM), and DNA-PK (662 nM). ATR-IN-20 exhibits excellent pharmacokinetic profile (F = 30%), and has anticancer effects .
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