1 Result for "

AVN211

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "AVN211" in MCE Product Catalog:

Cat. No.: HY-105998
CAS No.: 1173103-84-8
Target:  

5-HT Receptor

Domaines de recherche:  

Neurological Disease

AVN-211 (CD-008-0173) is a selective and orally active 5HT6R antagonist with an IC50 of 2.34 nM and a Ki of 1.09 nM. AVN-211 exhibits 5K-fold higher 5HT6R selectivity over other 65 receptors, enzymes, and ion channels. AVN-211 significantly improves cognitive and anxiety behaviors in various AD animal models, and has good safety profiles. AVN-211 can be used for the study of Alzheimer's dementia .
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