1 Result for "

Alectinib-d6

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Alectinib-d6" in MCE Product Catalog:

Cat. No.: HY-13011S1
CAS No.: 1616374-19-6
Purity:  98.05%
Synonyms: CH5424802-d6; RO5424802-d6; AF802-d6
Alectinib-d6 is deuterium labeled Alectinib. Alectinib (CH5424802) is a potent, selective, and orally available ALK inhibitor with an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively . Alectinib demonstrates effective central nervous system (CNS) penetration .
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