1 Result for "

Alectinib-d8

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Alectinib-d8" in MCE Product Catalog:

Cat. No.: HY-13011S
CAS No.: 1256585-15-5
Synonyms: CH5424802-d8; RO5424802-d8; AF802-d8
Alectinib-d8 is the deuterium labeled Alectinib. Alectinib (CH5424802) is a potent, selective, and orally available ALK inhibitor with an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively . Alectinib demonstrates effective central nervous system (CNS) penetration .
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