1 Result for "

Anthrax edema factor

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Anthrax edema factor" in MCE Product Catalog:

Cat. No.: HY-179376
Target:  

Bacterial

Research Areas:  

Infection

Anti-virulence factor-IN-3 (Compound 21) is a covalent β-aminosulfinyl type anthrax edema factor (EF) inhibitor, with a Ki value of 0.44 μM. Anti-virulence factor-IN-3 generates an active ethylene sulfinyl intermediate, which forms an irreversible covalent bond with the Lys residue at the active center of EF, permanently inhibiting the adenylate cyclase activity of EF. Anti-virulence factor-IN-3 effectively inhibits the cAMP production induced by EF, with an EC50 value of 0.15 μM. Anti-virulence factor-IN-3 can be used for research on anthrax Infection .
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