1 Result for "

Anticancer agent 340

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Anticancer agent 340" in MCE Product Catalog:

Cat. No.: HY-184865
CAS No.: 3032493-76-5
Research Areas:  

Cancer

Anticancer agent 340 is an orally active antitumor agent. Anticancer agent 340 can bind to both the androgen receptor (AR) and BRD4 protein simultaneously, dose-dependently inducing the formation of the AR-BRD4 ternary complex, inhibiting the expression of the downstream target gene HEXIM1 (Gene X), and activating the Caspase 3/7 pathway to initiate apoptosis. Its proliferation inhibition and apoptosis activities are both significantly AR expression-dependent. Anticancer agent 340 can be used to study AR/BRD4 driven malignancies such as castration-resistant prostate cancer (CRPC) .
loading...
    loading...