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Cat. No.: HY-184865

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Anticancer agent 340

Anticancer agent 340 is an antitumor compound. Anticancer agent 340 can be used to study AR/BRD4 driven malignancies such as castration-resistant prostate cancer (CRPC).

For research use only. We do not sell to patients.

CAS No.: 3032493-76-5
Formula: C₄₉H₅₁ClN₁₀O₄S
Molecular Weight:911.51

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (283 KB)

Anticancer agent 340 Chemical Structure

CAS No.: 3032493-76-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
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Biological Activity

Description

Anticancer agent 340 is an antitumor compound. Anticancer agent 340 can be used to study AR/BRD4 driven malignancies such as castration-resistant prostate cancer (CRPC)^[1].

All Caspase Isoforms :

In Vitro

Anticancer agent 340 (compound I-49) showed potent inhibitory activity against the proliferation of T-Rex 293 cell line SC cells, with a GI₅₀ < 0.5 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 3032493-76-5
Molecular Weight 911.51
Formula C₄₉H₅₁ClN₁₀O₄S
SMILES

CC(C)([C@H](C1(C)C)OC2=CC(Cl)=C(C=C2)C#N)[C@H]1NC(C3=CN=C(N=C3)N(CC4)CCC4(C5)CC5OC6=CC=C(C7=N[C@@H](CC8=NC=CO8)C9=NN=C(C)N9C%10=C7C(C)=C(C)S%10)C=C6)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (283 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Eastman KL, et al.; Halda Therapeutics Opco Inc., assignee. Synthetic RIPTAC AR and BRD4 dual degraders for castration-resistant prostate cancer. WO2024054603 A1. PCT International Application No. PCT/US2023/032252, filed 2023 Sep 8, published 2024 Mar 14.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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