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Pathways Recommended: Apoptosis
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Apoptosis inducer 57

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-180537
    Apoptosis inducer 57

    		Apoptosis Cancer
    Apoptosis inducer 57 is a apoptosis inducer and Thymidylate Synthase (TS) inhibitor. Apoptosis inducer 57 exhibits cytotoxic activity against SW480 and MCF-7 cancer cells with IC50 values of 15.7 and 16.5 µM, and induces dose-dependent apoptosis and S-phase cell cycle arrest. Apoptosis inducer 57 stalely binds the TS active site via interactions with Asp218 and Met311. TS-IN-9 can be used for breast cancer and colorectal cancer research .
    Apoptosis inducer 57

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