6 Results for "

Aur-0101

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "Aur-0101" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-12522S
CAS No.: 3020284-76-5
Purity:  99.37%
Synonyms: Aur0101-d8; Auristatin-0101-d8
PF-06380101-d8 (Aur0101-d8) is a deuterium labeled PF-06380101 (HY-12522). PF-06380101, an Auristatin microtubule inhibitor, is a cytotoxic Dolastatin 10 analogue .
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1
1 Cited Publications
Cat. No.: HY-128955
CAS No.: 1438849-92-3
Purity:  99.66%
Research Areas:  

Cancer

MC-VC-PABC-Aur0101 is a agent-linker conjugate for ADC with potent antitumor activity by using Aur0101 (an auristatin microtubule inhibitor), linked via the ADC linker MC-VC-PABC.
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Cat. No.: HY-12522
CAS No.: 1436391-86-4
Purity:  99.47%
Synonyms: Aur0101; Auristatin-0101
Research Areas:  

Cancer

PF-06380101 (Aur0101), an auristatin microtubule inhibitor, is a cytotoxic Dolastatin 10 analogue. PF-06380101 (Aur0101) shows excellent potencies in tumor cell proliferation assays and differential ADME properties when compared to other synthetic auristatin analogues that are used in the preparation of ADCs.
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Cat. No.: HY-P99829
CAS No.: 1869937-48-3
Synonyms: PF-06647020; ABBV-647; h6M24-vc0101
Cofetuzumab pelidotin (PF-06647020) is a PTK7-targeting ADC comprising a humanized anti-PTK7 mAb (hu6M024, IgG1) joined to an auristatin microtubule inhibitor payload, auristatin-0101 (Aur0101; HY-12522), by a cleavable valine-citrulline (vc)-based linker. Cofetuzumab pelidotin has a DAR of 4. Cofetuzumab pelidotin binds to cell-surface PTK7 with an EC50 of 1153 pM by flow cytometry. Cofetuzumab pelidotin has the potential for solid tumors research .
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Cat. No.: HY-111554
CAS No.: 1438851-17-2
Purity:  98.49%
AcLys-PABC-VC-Aur0101 is a agent-linker conjugate for ADC (anti-CXCR4 ADC) with potent antitumor activity by using Aur0101 (an auristatin microtubule inhibitor), linked via the cleavable linker AcLys-PABC-VC .
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Cat. No.: HY-48668
CAS No.: 1609108-48-6
Target:  

ADC Linkers

Research Areas:  

Cancer

AcLys-PABC-VC-Aur0101 intermediate-1 is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate .
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