1 Result for "

B 355252

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "B 355252" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-120553
CAS No.: 1261576-81-1
Purity:  ≥99.0%
Target:  

Apoptosis

Research Areas:  

Neurological Disease

B355252, a phenoxy thiophene sulfonamide small molecule, is a potent NGF receptor agonist. B355252 potentiates NGF-induced neurite outgrowth. B355252 protects ischemic neurons from neuronal loss by attenuating DNA damage, reducing ROS production and the LDH level, and preventing neuronal apoptosis. B355252 has anti-apoptotic effects in glutamate-induced excitotoxicity, as well as in a murine hippocampal cell line (HT22) model of Parkinson disease (PD) .
loading...
    loading...