1 Result for "

BI9740

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "BI9740" in MCE Product Catalog:

Cat. No.: HY-171888
CAS No.: 1628596-25-7
Target:  

Cathepsin Elastase

Research Areas:  

Inflammation/Immunology

BI-9740 is an orally active and selective cathepsin C (CatC) inhibitor, with an IC50 of 0.6 nM in mice and 2.6 nM in rats. BI-9740 can inhibit the production of active neutrophil elastase. Additionally, BI-9740 is capable of reducing the activities of neutrophil elastase and cathepsin G in the bone marrow of rats, alleviating pathological damage to grafts after heart transplantation, shortening the reperfusion time, and improving left ventricular function. BI-9740 can be used in research related to organ transplantation .
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