1 Result for "

BIBS39

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "BIBS39" in MCE Product Catalog:

Cat. No.: HY-19732
CAS No.: 133085-33-3
Target:  

Angiotensin Receptor

Research Areas:  

Cardiovascular Disease

BIBS 39 is a non-peptide angiotensin II receptor antagonist with antihypertensive activity, with higher affinity for the AT1 receptor than for the AT2 receptor. BIBS 39 competitively blocks AT1-mediated vasoconstriction and pressor responses, and effectively inhibits the activity of the renin-angiotensin-aldosterone system. BIBS 39 reduces diastolic blood pressure and induces mild, transient reflex tachycardia, with no off-target functional activity on the norepinephrine, K +/Cl or vasopressin pathways. BIBS 39 can be used in research related to hypertension and renal hypertension [1][2 ][3].
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