1 Result for "

BIO7488

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "BIO7488" in MCE Product Catalog:

Cat. No.: HY-162359
CAS No.: 2573211-25-1
Target:  

IRAK

BIO-7488 is an orally active, selective and blood-brain barrier permeable IRAK4 inhibitor, with an IC50 value of 0.5 nM. BIO-7488 inhibits the production of pro-inflammatory cytokines (IL-1β, TNFα, IL-6) and demonstrates anti-inflammatory effects in both LPS (HY-D1056) and distal hypoxic-middle cerebral artery occlusion (DH-MCAO) ischemic stroke model. BIO-7488 can be used for the study of neuroinflammatory-related diseases, particularly ischemic stroke .
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