1 Result for "

BKCa activator1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "BKCa activator1" in MCE Product Catalog:

Cat. No.: HY-170918
Target:  

Potassium Channel

Research Areas:  

Others

BKCa activator-1 (Compound 51b) is the orally active activator for the calcium-activated potassium channel BKCa with an EC50 of 2.82 μM. BKCa activator-1 increases K+ efflux, leads to cell membrane hyperpolarization, thereby inhibiting smooth muscle contraction. BKCa activator-1 alleviates urinary incontinence in spontaneously hypertensive rat (SHR) model, exhibits antitussive effect in puinea pig cough model .
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