1 Result for "

BRAF1 RBD

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "BRAF1 RBD" in MCE Product Catalog:

Cat. No.: HY-181965
CAS No.: 3023465-20-2
Target:  

Ras ERK p38 MAPK

Research Areas:  

Cancer

KRAS G12C-IN-78 is a selective SWII-binding KRASG12C dual inhibitor targeting both inactive and active states. KRAS G12C-IN-78 rapidly inhibits ERK1/2 phosphorylation, induces covalent adduct formation with endogenous KRASG12C, suppresses MAPK pathway gene expression, and inhibits cellular proliferation in KRASG12C mutant cells. KRAS G12C-IN-78 can be used for the research of KRASG12C mutant solid tumors, including pancreatic ductal adenocarcinoma and non-small cell lung cancer .
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