1 Result for "

Bax activator2

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Bax activator2" in MCE Product Catalog:

Cat. No.: HY-182349
CAS No.: 3034297-25-8
Research Areas:  

Cancer

Bax activator-2 is a pro-apoptotic agent targeting BAX, with an IC50 of 0.30 μM against human BAX. Bax activator-2 binds to the trigger site of BAX and induces its conformational change. Bax activator-2 induces mitochondrial depolarization, cytochrome c release, cleavage of caspase-3/9 and PARP, thereby initiating apoptosis. Bax activator-2 exhibits cytotoxicity against a variety of cancer cell lines. Bax activator-2 can be used in research related to acute myeloid leukemia and solid tumors .
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