1 Result for "

BiDAC

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "BiDAC" in MCE Product Catalog:

Cat. No.: HY-153341
CAS No.: 2882165-79-7
Purity:  99.41%
Synonyms: CFT1946
Target:  

PROTACs Raf

Research Areas:  

Cancer

Tagarafdeg (CFT1946) is an orally active, CRBN-based and mutant-selective bifunctional degradation activating compound (BiDAC) degrader of BRAF V600E with a DC50 of 14 nM in A375 cells. Tagarafdeg is capable of degrading BRAF V600E (Class I), G469A (Class II), G466V (Class III) mutations, and the p61-BRAF V600E splice variant. Tagarafdeg can be used in tumor research .
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