2 Results for "

C. comatus

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "C. comatus" in MCE Product Catalog:

Coccinin
Coccinin
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Cat. No.: HY-P11176
CAS No.: 1177990-16-7
Target:  

Fungal HIV

Research Areas:  

Infection

Coccinin is an antifungal peptide. Coccinin can be purified from the seeds of large scarlet runner beans. Coccinin inhibits HIV-1 reverse transcriptase. Coccinin shows antifungal activity against M. arachidicola, F. oxysporum, P. piricola, B. cinerea, C. comatus and R. solani, with IC50s of 75, 81, 89, 109, 122 and 134 μM, respectively .
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8-Bromo-2'-deoxyguanosine-13C,15N2
8-Bromo-2'-deoxyguanosine-13C,15N2
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Cat. No.: HY-W767399
8-Bromo-2'-deoxyguanosine- 13C, 15N2 is the 13C- and 15N-labeled 8-Bromo-2'-deoxyguanosine (HY-W011168). 8-Bromo-2'-deoxyguanosine is an inflammation-related DNA halogenated adduct and an early biomarker of inflammation-induced oxidative tissue damage. The formation of 8-Bromo-2'-deoxyguanosine precedes that of oxidative and nitrative products, and it can be generated via the MPO-H2O2-Cl --Br - system. 8-Bromo-2'-deoxyguanosine serves as the immunogen for preparing the monoclonal antibody mAb8B3, which can be used to detect early DNA modifications in preclinical models; its urinary level also increases significantly in inflammatory disease models. 8-Bromo-2'-deoxyguanosine can also be produced in the dermis of UV-B irradiated mice, and the extract of Coprinus comatus significantly reduces its level. 8-Bromo-2'-deoxyguanosine finds applications in studies related to inflammatory diseases, diabetes, hepatocellular carcinoma, and UV-B induced skin inflammation .
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