4 Results for "

CA-170

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "CA-170" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-101093
CAS No.: 1673534-76-3
Purity:  99.39%
Target:  

PD-1/PD-L1

Research Areas:  

Inflammation/Immunology Cancer

CA-170 is an orally delivered dual inhibitor of VISTA and PD-L1. CA-170 exhibits potent rescue of proliferation and effector functions of T cells inhibited by PD-L1/L2 and VISTA with selectivity over other immune checkpoint proteins as well as a broad panel of receptors and enzymes .
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Cat. No.: HY-P11253
Target:  

VISTA

Research Areas:  

Inflammation/Immunology

DOTA-Bn-CA-170 is a molecular probe targeting the VISTA protein, with a Kd value of 0.124 nM. DOTA-Bn-CA-170 is formed by covalently linking the p-SCN-Bn-DOTA ligand with CA-170 (HY-101093). DOTA-Bn-CA-170 labeled with [ 68Ga]Ga successfully achieves specific and high-contrast PET imaging of VISTA expression in various tumor-bearing mouse models. DOTA-Bn-CA-170 can be used for the study of VISTA-targeted immunotherapy .
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Cat. No.: HY-101093R
CAS No.: 1673534-76-3
CA-170 (Standard) is the analytical standard of CA-170 (HY-101093). This product is intended for research and analytical applications. CA-170 is an orally delivered dual inhibitor of VISTA and PD-L1. CA-170 exhibits potent rescue of proliferation and effector functions of T cells inhibited by PD-L1/L2 and VISTA with selectivity over other immune checkpoint proteins as well as a broad panel of receptors and enzymes .
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Cat. No.: HY-P11252
Research Areas:  

Cancer

DOTA-CA-170 is a DOTA-modified VISTA targeting agent CA-170. DOTA-CA-170 can be radiolabeled. DOTA-CA-170 can be used in the research of visualizing and distinguishing VISTA expression .
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