4 Results for "

CDK1/CCNB1

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "CDK1/CCNB1" in MCE Product Catalog:

  • Targets Recommended:
Referencia número: HY-114779
No. CAS: 158982-15-1
Pureza:  99.34%
Target:  

CDK

Áreas de investigación:  

Cancer

N9-Isopropylolomoucine is a mitotic cyclin dependent kinase (CDK) inhibitor. N9-Isopropylolomoucine targets CCNB 1/CDK1 and can be used for cancer research [1].
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Referencia número: HY-P11028
Target:  

CDK

Áreas de investigación:  

Cancer

M1-20 is a CDK1 inhibitor. M1-20 promotes CDK1 ubiquitination by CUL4-DDB1-DCAF1 complexes and degradation through the proteasome pathway. M1-20 abolishes the formation of CDK1/CCNB1 complexes. M1-20 has significant anticancer activity of spontaneous breast cancer in FVB/N MMTV-PyVT mice model [1].
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Referencia número: HY-162895
Áreas de investigación:  

Cancer

NL13 is a Polo-like kinase 4 (PLK4) inhibitor with an IC50 value of 2.32 μM. NL13 can inhibit the viability of PC3 and DU145 prostate cancer cells, with IC50 values of 3.51 μM and 2.53 μM, respectively. NL13 can lead to the inactivation of the AKT signaling pathway by downregulating CCNB1/CDK1, inducing G2/M cell cycle arrest, and triggering apoptosis through the cleavage of caspase-9/caspase-3. In prostate cancer mice, NL13 can inhibit tumor growth [1].
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Referencia número: HY-P702736
Pureza:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK1; Cell Division Protein Kinase 1; Prev. CDC2; P34 Protein Kinase; CDC28A; P34CDC2; Cell Division Cycle 2, G1 To S And G2 To M; Cell Cycle Controller CDC2; Cell Division Control Protein 2 Homolog; CDKN1; Cyclin Dependent Kinase 1; Cyclin-Dependent Kina
Species:  
Source:  
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