1 Result for "

CDK2-IN-60

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "CDK2-IN-60" in MCE Product Catalog:

Cat. No.: HY-184649
CAS No.: 2922859-30-9
Target:  

CDK

Research Areas:  

Cancer

CDK2-IN-60 is an orally active, ATP-competitive selective CDK2 inhibitor with a Ki of 77 pM. CDK2-IN-60 has high selectivity for both CDK4 and CDK1. CDK2-IN-60 blocks G1/S cell cycle progression to suppress proliferation of CCNE1-amplified tumor cells. CDK2-IN-60 serves as a lead chemical probe for investigating CCNE1-amplified cancers and CDK4/6 inhibitor-resistant HR-positive breast cancer .
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