1 Result for "

CFT743

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "CFT743" in MCE Product Catalog:

Cat. No.: HY-182577
CAS No.: 2154350-81-7
Research Areas:  

Cancer

CFT-743, a PROTAC-based heterobifunctional degrader and BET inhibtor, is a degrader of BRD4 bromodomain 1 (BD1) with a DC50 of 4.3 nM. CFT-743's antitumor activitiy is dependent on BET degradation and can be attenuated by Pomalidomide (HY-10984), which is a CRBN binding molecule. CFT-743 induces ubiquitination of BRD4 BD1. CFT-743 can be used for cancer research .
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